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Bay 41-4109

CAS No. 298708-81-3

Bay 41-4109 ( Bay-414109 )

Catalog No. M13917 CAS No. 298708-81-3

A potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Bay 41-4109
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM.
  • Description
    A potent, non-nucleosidic inhibitor of HBV nucleocapsid maturation with IC50 of 0.05 uM; reduces HBV core protein levels in cell culture, possess in vitro and in vivo antiviral activity. HBV infection Discontinued
  • Synonyms
    Bay-414109
  • Pathway
    Microbiology/Virology
  • Target
    HBV
  • Recptor
    HBV
  • Research Area
    Infection
  • Indication
    HBV Infection

Chemical Information

  • CAS Number
    298708-81-3
  • Formula Weight
    395.76
  • Molecular Formula
    C18H13ClF3N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 44 mg/mL
  • SMILES
    O=C(C1=C(C)NC(C2=NC=C(F)C=C2F)=N[C@H]1C3=CC=C(F)C=C3Cl)OC
  • Chemical Name
    5-Pyrimidinecarboxylic acid, 4-(2-chloro-4-fluorophenyl)-2-(3,5-difluoro-2-pyridinyl)-1,4-dihydro-6-methyl-, methyl ester, (4R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Deres K, et al. Science. 2003 Feb 7;299(5608):893-6.
2. Weber O, et al. Antiviral Res. 2002 May;54(2):69-78.
3. Brezillon N, et al. PLoS One. 2011;6(12):e25096.
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